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Aptivus (Tipranavir)
Manufactured by: Boehringer Ingelheim  This product requires a valid prescription
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Aptivus (Tipranavir) is an anti-HIV medication. Aptivus (Tipranavir) is in a category of HIV medicines called protease inhibitors (PIs). Aptivus (Tipranavir) prevents cells infected by HIV from producing new virus which reduces the amount of virus in your body.
Aptivus (Tipranavir) must be used in combination with Norvir (ritonavir) and at least two other anti-HIV drugs.
Aptivus (Tipranavir), manufactured by Boehringer Ingelheim, is approved for the treatment of HIV by the U.S. Food and Drug Administration.
Aptivus (Tipranavir) is only approved for HIV-infected people who have tried and failed other anti-HIV drug regimens (including those containing protease inhibitors) in the past. Aptivus (Tipranavir) is not approved for HIV-infected people starting anti-HIV treatment, or a protease inhibitor, for the first time (unless they were infected with a strain of HIV resistant to multiple protease inhibitors).
The correct dose of Aptivus (Tipranavir) is 500mg twice a day (two 250mg capsules twice daily) . To help keep levels of Aptivus (Tipranavir) high in the blood, which is very important for the drug to be effective, it is necessary to combine Aptivus with low doses (200mg twice daily) of the protease inhibitor Norvir (ritonavir).
The following medications should not be taken while you are being treated with Aptivus or ritonavir:
Antifungals: Vfend (voriconazole)
Acid reflux/heartburn medications: Propulsid (cisapride)
Antibiotics: Rifadin (rifampin)
Antimigraine medications: Methergine, Methylergometrine (methylergonovine); Ergostat, Cafergot, Ercaf, Wigraine (ergotamine); Ergotrate, Methergine (ergonovine); or D.H.E. 45, Migranal (dihydroergotamine)
Antihistamines: Hismanal (astemizole) or Seldane (terfenadine)
Heart medications: Cordarone (amiodarone), Vascor (bepridil), Tambocor (flecainide), Rythmol (propafenone), or Quinaglute/Quinidex (quinidine)
Cholesterol-lowering drugs (statins): Zocor (simvastatin) and Mevacor (lovastatin)
Antipsychotics: Orap (pimozide)
Sedatives: Versed (midazolam) and Halcion (triazolam)
Enlarged prostate: Uroxatral (alfuzosin)
Herbal products: St. John's wort
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