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Dovobet (Calcipotriol/Betamethasone Dipropionate Ointment)
Manufactured by: Leo  This product requires a valid prescription
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Dovobet is unsuitable for the scalp, and extra caution should be exercised if it is used on the face and genital area because of the potency of the steroid. It is not licensed for use in patients under 18 years of age or pregnant females.
Dovobet should only be used for a maximum of four weeks and not more than 100g should be used per week. Once-daily is almost as effective as twice-daily (see Efficacy below). The improvement achieved can often be maintained with open-ended use of Dovonex after a course of Dovobet is completed.
Dovobet ointment contains two active ingredients, betamethasone dipropionate and calcipotriol hydrate.
Calcipotriol is a medicine that is a derivative of vitamin D. When applied to the skin it works by reducing the production of skin cells.
In psoriasis, the scaling and thickening of the skin and the appearance of raised plaques are the result of excessive skin cell production in this disease. Calcipotriol reduces the excessive skin cell production and helps improve these symptoms of psoriasis.
Betamethasone is a type of medicine called a corticosteroid. Corticosteroids are medicines used for reducing inflammation. Skin inflammation in psoriasis occurs due to the irritation of the skin, and is caused by the release of various substances important in the immune system. These substances cause blood vessels to widen, resulting in the affected area becoming red, swollen, itchy and painful.
When betamethasone is applied to the skin it works by acting inside the cells to decrease the release of these inflammatory substances. This reduces swelling, redness and itch. Betamethasone is a potent corticosteroid.
The combination of medicines in this ointment is used to treat stable plaque psoriasis. The ointment should be applied once a day, initially for four weeks. If your psoriasis gets worse again after you stop treatment, the medicine can used for longer to keep the psoriasis under control. However, repeated or prolonged treatment must only be used on the advice and under the supervision of your doctor.
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