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Drug Overview
Fragmin belongs to the family of an anticoagulant drug known as blood thinner drug and commonly used for the prevention and treatment of those patients who suffered to the problems of blood clot that has formed within a blood vessel or in the lungs and blood clots associated with certain heart conditions or replacement of a heart valve. Fragmin works and thins the blood by changing the body's clotting system.
Fragmin helps to prevent formation of clots in the veins, arteries, lungs, or heart during abdominal surgery. Fragmin treatment and prevention of blood clots in the veins of the leg (deep vein thrombosis), lungs (pulmonary embolism)and coronary artery disease.
Fragmin always takes under doctor’s guidance. Do not take more of it and do not take it for a longer time than your doctor ordered. The recommended doses of Fragmin will be different for different patients, according to the requirements of each patient; you continue to take it for as long as your doctor prescribes, even if you do not feel an immediate benefit. If you can not tolerate the recommended dosage, your doctor can prescribe a dose that sufficient for you. Fragmin is also available in generic form Dalteparin sodium Injection. Fragmin is being manufactured by Pharmacia & Upjohn Pharmaceuticals and available in Injection. Fragmin may also be used for relieve other conditions that determined by your doctor or consultant.
Effects - How it works in the body
Fragmin belongs to the family of an anticoagulant drug known as blood thinner drug and commonly used for the prevention and treatment of those patients who suffered to the problems of blood clot that has formed within a blood vessel or in the lungs and blood clots associated with certain heart conditions or replacement of a heart valve. Fragmin works and thins the blood by changing the body's clotting system. Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. The clotting process is complicated and begins when blood cells called platelets clump together and produce chemicals that activate the clotting process. The final part of this process involves a substance known as thrombin being activated to produce a protein called fibrin. Fibrin binds the platelets together, forming a blood clot. This is the body’s natural way of repairing itself. Sometimes, however, a blood clot can form abnormally within the blood vessels known as a thrombus. It can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. The embolus may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. This is known as a thromboembolism. Some people have an increased tendency for blood clots to form within the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels. Slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). These clots can break off and travel to the lungs (pulmonary embolism). Fragmin is used to prevent and treat these types of abnormal blood clots. It works by inactivating thrombin in the clotting process described as above. This stops the formation of fibrin, the essential component of blood clots.
Side effects
Possible side effects during the uses of Fragmin:
- Allergic reactions
- Abdominal or stomach pain
- Bleeding of gums
- Coughing up blood
- Difficulty in breathing or swallowing
- Dizziness
- Headache
- Increased menstrual flow or vaginal bleeding
- Nosebleeds
- Paralysis
- Prolonged bleeding from cuts
- Red or dark brown urine
- Tarry stools
- Shortness of breath
- Unusual bruising
- Vomiting of blood
- Back pain
- Bleeding from mucous membranes
- Coughing
- Feeling faint
- Fever
- Leg weakness
- Numbness
- Problems with bowel or bladder function
- Skin rash
- Hives or itching
- Sloughing of skin at place of injection
- Swelling of eyelids, face, or lips
- Tightness in chest or wheezing
- Unusual tiredness or weakness
- Yellow eyes or skin
Interactions
Although certain medicines should not be used together at all, so its your responsibilities that tell your doctor or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also you tell your doctor or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or addicted to illegal drugs. These may affect the working mechanism of Fragmin. In these cases, your doctor may change the dose or teach precautions may be necessary. Therefore when you are taking Fragmin, it is most important that your doctor or health care professional know if you are taking any of the following or other drugs:
- Alcohol
- Aspirin and Aspirin-like medicines
- Inflammation or pain medicine or Ticlopidine
- Antiinflammatory drugs such as ibuprofen or Motrin
- Naproxen or Aleve
- Ketoprofen or Orudis-KT
- Cilostazol
- Clopidogrel
- Dipyridamole
- Ticlopidine
- Warfarin
Counterindications
You shouldn’t use this medicine without consultation of doctor if you have an allergy to Fragmin or any other ingredients of this medicine.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the problem of heart disease or circulation problems.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the problem of liver disease.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the problems of kidney disease.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the problems of bleeding disorders, hemorrhage, or hemophilia.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the problems of brain tumor or aneurysm.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the problems of ulcer in the stomach or intestine.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the Cancer of the internal organs.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the Diabetes mellitus or sugar diabetes.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the problems of diverticulitis or other bowel disease.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to the problems of Hypertension (high blood pressure) and Stroke.
You shouldn’t use Fragmin without consultation of doctor if you are pregnant or plan to be pregnant.
You shouldn’t use Fragmin without consultation of doctor if you are suffering to breastfeeding.
Similar drugs of Fragmin
- Dalteparin sodium
- Acenocoumarol
- Anisindione
- Dicumarol
- Miradon
- Coumadin
- Warfilone
- Warfarin
Major drug Manufacturers
- Pharmacia & Upjohn Pharmaceuticals
- Paladin Pharmaceuticals
- Pendopharm Inc.
- Alliance Pharmaceuticals
- Schering Corp., Kenilworth, NJ
- Abbott Pharmaceuticals
- Merck Pharmaceuticals & Co.
- MACROBID Pharmaceuticals
From where can one get Fragmin?
Anyone can buy Fragmin from Online Canadian Pharmacy, which is available at a discounted price, 50% off, in Canada, and the best way to get Fragmin is by logging on to http://www.canadiandrugswholesale.com for online orders. This pharmacy provides you with drugs at cheap and affordable prices. One can order the medicine and pay through VISA, MasterCard or international money order.
Why to buy Fragmin drug from Canada?
It is cheaper to buy Fragmin from Online Canadian Pharmacy, because Canadian government regulates the prices of Fragmin and also because of the very common reason of exchange rate. Since, the Canadian dollar is cheaper as compared to the US Dollars, so one can buy more Fragmin from Canada, there by saving a lot of money.
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