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Zemplar (Paricalcitol Capsules)
Manufactured by: Abbott  This product requires a valid prescription
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Zemplar is used to prevent and treat high parathyroid hormone levels in patients with chronic kidney failure.
You should not take Zemplar if you have signs of toxic levels of vitamin D or an abnormally high amount of calcium in your blood.
It is important for you and your doctor to be aware of the symptoms of too much calcium, (e.g., weakness, headache, excessive sleepiness, nausea, vomiting, dry mouth, constipation, muscle spasm or bone pain). If you have these symptoms, your doctor may want to lower the dose of Zemplar or stop the drug until your calcium level returns to normal.
Your doctor will monitor you closely if you are taking the drug digoxin along with Zemplar.
Zemplar is administered as an injection during dialysis treatment, no more than every other day.
In order to ensure Zemplar’s effectiveness, diet is important. Your doctor may want you to:
limit your intake of foods and drugs containing phosphorous
avoid foods and drugs containing aluminum
Zemplar Side Effects (not a complete list):
Chills
Not feeling well
Fever
Flu
Infection
Increase frequency or pounding of heart
Dry mouth
Blood in stool
Nausea
Vomiting
General swelling
Light-headedness
Pneumonia
Zemplar is a vitamin D receptor activator which suppresses PTH through its direct action on the parathyroid gland with minimal impact on calcium and phosphorous homeostasis.
Zemplar was discovered by Dr. Hector DeLuca in 1985 and was approved by the
FDA on April 17, 1998.
Zemplar is designed specifically for secondary hyperparathyroidism associated with CKD stage
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