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Boniva (Ibandronate Sodium Tablets and Injections)
Manufactured by: Glaxo Smith Kline  This product requires a valid prescription
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Boniva is used to treat or prevent osteoporosis in women after menopause. Boniva may increase bone mass by slowing loss of bone in most women who take it, even though they won’t be able to see or feel a difference. Boniva may help lower the chances of breaking bones (fractures). For Boniva to treat or prevent osteoporosis, you have to take it as prescribed. Boniva will not work if you stop taking it.
You should not take Boniva if you:
have low blood calcium (hypocalcemia).
cannot sit or stand up for at least 1 hour (60 minutes) after taking Boniva.
have kidneys that work very poorly.
are allergic to ibandronate sodium or any of the other ingredients of Boniva.
Boniva tablets(ibandronate sodium) is an oral drug that is used for treating osteoporosis. Boniva tablets(ibandronate sodium) is in a class of drugs called bisphosphonate that includes alendronate (Fosamax) and risedronate (Actonel), both of which are orally available which can be taken daily or weekly. Boniva tablets(ibandronate sodium) may be taken daily, but it is the only oral biphosphonate that is approved to be taken monthly. There are also several injectable bisphosphonate, etidronate (Didronel), pamidronate (Aredia)] and zoledronate (Zometa), which can also be used to prevent or treat osteoporosis and which may be given every three months or yearly. All of the bisphosphonates prevent the breakdown of bone by bone cells called osteoclasts. In persons who are at high risk for osteoporosis, bisphosphonates not only result in increased amounts of bone and bone strength, they also reduce the risk of hip fractures and other bone fractures.
Boniva tablets (ibandronate sodium) should be stored at room temperature, 15-30°C (59-86°F). Keep Boniva tablets(ibandronate sodium) away from the reach of children.
Boniva tablets (ibandronate sodium)are used to prevent and to treat osteoporosis in women after the menopause.
The dose of Boniva tablets (ibandronate sodium) is 2.5 mg once daily or 150 mg once monthly. If monthly dosing is used, the Boniva tablets (ibandronate sodium) should be taken on the same day of each month. Boniva tablets (ibandronate sodium) should be taken at least 60 minutes before the first food or drink of the day (other than plain water) or before other oral medication, because of concern that that food or medication will interfere with the absorption of ibandronate. (Absorption of ibandronate from the intestine is poor, and any potential further decrease in absorption by food or medications needs to be avoided.) Boniva tablets (ibandronate sodium) also should be swallowed whole with six to eight ounces of plain water while in an upright position, in order to be certain that the tablets enter the stomach. (If the tablets stick in the esophagus they can irritate the esophagus.) For the same reason, one should not lie down for 60 minutes after taking ibandronate. (Tablets are more likely to stick in the esophagus when lying down.) Boniva tablets (ibandronate sodium) should not be chewed or sucked in order to avoid irritation of the mouth and throat.
Tell your health care provider if you:
-are pregnant or planning to become pregnant.
-are breast-feeding.
-have swallowing problems or other problems with your esophagus (the tube that connects your mouth and stomach).
-have kidney problems.
Tell your health care provider about all the medicines you take including prescription and non-prescription medicines, vitamins and supplements. Some medicines, especially certain vitamins, supplements, and antacids can stop Boniva from getting to your bones. This can happen if you take other medicines too close to the time that you take Boniva.
Stop taking Boniva and call your health care provider right away if you have:
-pain or trouble with swallowing
-chest pain
-very bad heartburn or heartburn that does not get better
Common side effects with Boniva are:
-diarrhea
-pain in extremities (arms or legs)
-upset stomach (dyspepsia)
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