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Oxsoralen-ultra (methoxsalen capsules)

Oxsoralen-ultra (methoxsalen capsules)

Manufactured by: ICN Pharmaceuticals

This product requires a valid prescription

 
Type Strength   Quantity   Price (USD)  
  Brand 10mg 100 Capsules $166.74  BUY
  Brand 10mg 200 Capsule $264.49  BUY
BUY CHEAP OXSORALEN-ULTRA FROM CANAD!

Oxsoralen (methoxsalen) is for the treatment of severe psoriasis. Certain skin problems present a unique set of challenges that can evoke a wide range of personal responses. Among the many diseases are psoriasis, producing red and scaly patches; vitiligo, a disease in which skin color is lost; and mycosis fungoides, a type of lymphoma. Methoxsalen, the active ingredient in Oxsoralen-Ultra, belongs to the group of compounds called psoralens. It is used along with ultraviolet light (found in sunlight and some special lamps) in a treatment call PUVA (Psoralen plus UVA) to treat psoriasis and vitiligo. Methoxsalen is also used together with ultraviolet light in photopheresis, used to treat the white blood cells associated with mycosis fungoides.

PUVA is an acronym for Psoralen plus UVA light and is a special type of phototherapy that combines the use of the drug Oxsoralen Ultra (methoxsalen) with exposure of the skin to UVA (ultraviolet A) light. Oxsoralen Ultra (methoxsalen) capsules make the skin more sensitive to light.

Ultraviolet A light is composed of the longest wavelengths in the ultraviolet spectrum. However, UVA light does have the property of being able to react with light-activated chemicals in the skin, or so-called photosensitizing agents. Psoralens, such as those present in Oxsoralen Ultra (methoxsalen), are photosensitizing compounds that are activated by UVA light. If they are present in the skin at the time of exposure to UVA light, they greatly increase the effect of the light on the skin. This increased sensitivity is the key to the beneficial effect of PUVA therapy.

PUVA is an effective therapy for severe recalcitrant psoriasis. Another benefit of PUVA therapy is that it tends to induce long-term remissions in psoriasis.

Your doctor will prescribe the appropriate number of Oxsoralen-Ultra (Methoxsalen Capsules, USP, 10mg) capsules to take before a PUVA treatment. Be sure to always take the exact dosage prescribed. Swallow the capsules with low-fat food or milk 1.5 to 2 hours before your appointment.

The PUVA treatment should only take place in your doctor's office, where you will stand in a special lighted area or booth for a short period of time. (A hand-held light unit may be used for smaller body areas.) In the PUVA treatment area, you will be surrounded by light bulbs that deliver special UVA light. You will be unclothed or partially clothed (depending on the size of the area to be treated) and you must wear UVA protective goggles, which will be provided by your doctor. Male genitalia must be shielded unless the area is being treated for psoriasis. Other sensitive areas such as the face, lips and breasts may also require protection. Treatment time may last from a few seconds to over 10 minutes and may vary from one treatment to the next.

Psoriasis sufferers who have been treated unsuccessfully with conventional treatments are candidates for PUVA therapy. PUVA therapy involves the ingestion of Oxsoralen-Ultra (Methoxsalen Capsules, USP, 10mg) 1.5 to 2 hours prior to exposure to UVA light. The dose of Oxsoralen-Ultra capsules you take is held constant and is determined by your weight. The interval between taking Oxsoralen-Ultra capsules and being exposed to light is also held constant because peak levels of psoralen are usually reached in the skin between 1.5 to 2 hours after ingestion.

The variable in PUVA therapy is the dose of UVA light you are given. The initial dose is low and may be determined by your past history of sunburning and suntanning, or by testing your response to PUVA. The dose of UVA light is gradually increased in subsequent treatment as your tolerance to the treatment increases.

The dose of UVA light delivered during PUVA therapy is measured in joules per square centimeter (a measure of energy) and is translated into a given number of minutes of treatment. The output of the treatment units varies over time and different units emit different amounts of energy. Therefore, even if your dose of UVA light is constant, your treatment times may vary. Treatments will be required two to three times each week until your skin disease has cleared. Less frequent treatment is necessary to maintain a clear state. Most patients develop a tan or deepening of their normal skin pigmentation from PUVA therapy. The tanning may be uneven at first, with skin color lighter in areas affected by psoriasis. Some patients also develop freckles — particularly dark freckles — in areas affected by psoriasis. Burning from light treatment is a potential serious side effect of PUVA therapy. Regardless of how carefully light treatment is administered, some redness is likely to occur, especially at the beginning of therapy. If you experience any degree of redness or burning following treatment, be sure to alert your medical provider. The light dose may need to be lowered or you may need to skip a treatment. The most common side effects of PUVA therapy are:

Skin Burning. Serious burns from either UVA or sunlight (even through a window glass) can result if the recommended dosage of the drug and/or exposure schedules are exceeded.
Sunburn. Some redness is likely to occur in the skin at the beginning of PUVA therapy.
Pigmentation. Many patients observe pigmentation or tanning of their skin.
Nausea. Nausea may occur after taking the Oxsoralen-Ultra (Methoxsalen Capsules, USP, 10mg) capsules. This may be avoided or lessened by taking the medication with milk or grain-type foods such as crackers, toast or bagels, or by taking the drug just after a meal.
Itching. Itching commonly occurs as a result of light treatment. Numerous ointments are available to soothe mild itching. It is important to make your medical provider aware of any itching you have. With severe itching, it may be necessary to lower the light dose or skip a treatment. Call your medical provider before taking your capsules if itching is severe.
Dry skin. If PUVA therapy leads to dry skin, apply a moisturizing lotion while your skin is still damp after showering or bathing. If the moisturizer does not relieve your dry skin, ask your medical provider for other recommendations.
Friction blisters. Blisters are a fairly common occurrence, particularly on the hands and feet.
Ankle edema. A small number of patients develop swelling of the ankles as the first sign of phototoxicity.
Aggravation of skin disease. PUVA can sometimes aggravate and worsen the skin disease.
Increased hair growth. Hypertrichosis, or an increased growth of hair, particularly on the face, is an occasional side effect.

The total number of treatments depends on your diagnosis. In the beginning, treatments will be necessary two to three times per week. Eventually, the number decreases to a maintenance schedule or reaches a point at which you can stop completely if your skin remains clear. Your treatment must be spaced so that at least 48 hours elapse between sessions. The average course of treatment lasts approximately 12 weeks. PUVA therapy clears or dramatically improves psoriasis in over 84% of patients and can lead to extended remissions. Once your skin has cleared, you may continue PUVA therapy on a maintenance schedule of once a week, and then gradually decrease your treatments to one per month if your skin remains clear. If it is still clear after three to four months of maintenance therapy, you may discontinue PUVA therapy. If you experience a flare-up, therapy will be reinstated two to three times a week.

Long-term effects associated with PUVA therapy:

Skin cancer. Some people are at a higher risk than the normal population for developing skin cancer, including people who have had previous non-melanoma skin cancer, arsenic therapy or X-ray therapy to the skin, as well as individuals with extremely light complexions which always burn and never tan. In general, these patients are not considered for PUVA therapy unless strong extenuating circumstances exist in favor of it. For all other patients, there may be a minimally higher incidence of skin cancer. Because it is impossible to know exactly how much light a patient needs in order to produce a skin cancer, your skin should frequently be examined for abnormal growths throughout your PUVA therapy.
Cataracts. Animal studies show that cataracts may be produced as a result of excess PUVA therapy when no eye protection is used. If a patient undergoing PUVA therapy does not carefully protect his or her eyes by wearing appropriate protective sunglasses, there may be a risk of developing cataracts. To date, very few eye problems have been experienced with our patients since most are conscientious about following the simple instructions for eye protection during and following PUVA therapy. Pre-treatment eye exams and yearly followup exams are also required.

Shielding the eyes after Oxsoralen-Ultra capsule ingestion and for 24 hours thereafter during daylight hours is an absolute requirement. Make sure you wear special wraparound sunglasses that absorb ultraviolet light or block it entirely. These special sunglasses should be worn when you are outdoors, riding in a car or sitting near a window. Do not attempt to drive in dim light while wearing dark glasses. On non-treatment days, you should routinely wear either plastic wraparound or UVA-blocking sunglasses. Prescription sunglasses should be checked for their ability to block UVA light. This check may be performed at the phototherapy unit by your phototherapist. Do not allow your skin or lips to be exposed to sunlight for eight hours after treatment. In addition, do not expose your skin to either sunlight or sunlamps within 24 hours of treatment. It is advisable to wear protective clothing (i.e., hat, gloves, long sleeves) to cover as much of your body as possible, and to use a UVA-blocking sunscreen product with a sun protection factor (SPF) of at least 15. You must not sunbathe for 24 hours before and after PUVA therapy.

 

Oxsoralen-ultra

Oxsoralen-ultra is belongs to the family of drugs known as a psoralens drug and commonly used for the treatment of disease in which skin color is lost, and psoriasis, a skin condition associated with red and scaly patches. Oxsoralen-ultra/Methoxsalen works by restoring colour to the affected areas. Oxsoralen-ultra is comes in the category of drugs called also Methoxsalen. Oxsoralen-ultra is being manufactured by Valeant Pharmaceuticals and is available in 10mg Capsule.

What are the most common problems for which Oxsoralen-ultra/Methoxsalen is used?

Oxsoralen-ultra/Methoxsalen is useful for the treatment of vitiligo, a disease in which skin color is lost, and psoriasis, a skin condition associated with red and scaly patches.

Oxsoralen-ultra/Methoxsalen is also used with ultraviolet light in the treatment of white blood cells.

Oxsoralen-ultra/Methoxsalen is useful for those patients who suffered to the problems of Eczema.

Oxsoralen-ultra/Methoxsalen is useful for those patients who suffered to the problems of Alopecia areata.

Oxsoralen-ultra/Methoxsalen is useful for those patients who suffered to the problems of inflammatory dermatoses.

Oxsoralen-ultra/Methoxsalen is useful for those patients who suffered to the problems of Lichen planus.

Oxsoralen-ultra/Methoxsalen is useful for those patients who suffered to the problems of Mycosis fungoides, which is a type of lymphoma.

Oxsoralen-ultra/Methoxsalen is useful for those patients who suffered to the problems of Psoriasis.

Oxsoralen-ultra/Methoxsalen may also be used for relieve other conditions that determined by your doctor’s or consultant.

How does Oxsoralen-ultra/Methoxsalen work?

Oxsoralen-ultra/Methoxsalen is belongs to the family of drugs known as a psoralens drug and commonly used for the treatment of disease in which skin color is lost, and psoriasis, a skin condition associated with red and scaly patches. Oxsoralen-ultra/Methoxsalen works by restoring colour to the affected areas. For psoriasis and atopic dermatitis, Oxsoralen-ultra/Methoxsalen is used in combination with high intensity UVA light therapy. Do not stop taking Oxsoralen-ultra/Methoxsalen without consulting your doctor.

Is any prescription required to get Oxsoralen-ultra/Methoxsalen?

Yes, prescription is necessary, one most not to use Oxsoralen-ultra/Methoxsalen without prescription. Some times in such conditions Oxsoralen-ultra/Methoxsalen is more harmful for health so, it is better to use Oxsoralen-ultra/Methoxsalen under doctor’s guidance or according to your medical consultant.

Dosages of Oxsoralen-ultra/Methoxsalen?

Oxsoralen-ultra/Methoxsalen Capsule always takes under doctor’s guidance. The recommended doses of Oxsoralen-ultra/Methoxsalen Capsule will be different for different patients, according to the requirements of each patient; you continue to take it for as long as your doctor prescribes, even if you do not feel an immediate benefit. Oxsoralen-ultra/Methoxsalen works best when taken long term. Your doctor will start you on a low dose of Oxsoralen-ultra/Methoxsalen and gradually increase your dose. If you can not tolerate the recommended dosage, your doctor can prescribe a dose that sufficient for you. Always take Oxsoralen-ultra/Methoxsalen with food or milk and a full glass of water.

What is the minimum duration for which Oxsoralen-ultra/Methoxsalen should be taken?

The duration of taking Oxsoralen-ultra/Methoxsalen is not constant; it depends according to the problem. Your doctor or consultant can describe you better about the time period for which duration Oxsoralen-ultra/Methoxsalen should be taken or until the medication is deemed effective. Your dose may need to be gradually decreased by your doctor.

Are there any side effects of Oxsoralen-ultra/Methoxsalen?

Possible side effects that occur during the uses of Orap/Pimozide:

  • Itching of skin
  • Nausea
  • Dizziness
  • Headache
  • Mental depression
  • Nervousness
  • Trouble in sleeping
  • Stomach upset
  • Sleeplessness
  • Rash
  • Mouth sores
  • Fever blisters
  • Fluid retention
  • Leg cramps

Under what circumstances Oxsoralen-ultra/Methoxsalen should not be used?

If you have an allergy to Oxsoralen-ultra/Methoxsalen Capsule or any other ingredients of this medicine, then should not be used.

If you have suffering to the problem of Heart disease, Oxsoralen-ultra/Methoxsalen Capsule should not be used without consulting of doctor.

If you have suffering to the problem of Allergy to sunlight, Oxsoralen-ultra/Methoxsalen Capsule should not be used without consulting of doctor.

If you have suffering to the problem of blood vessel disease, Oxsoralen-ultra/Methoxsalen Capsule should not be used without consulting of doctor.

If you have suffering to the problem of Infection or Lupus erythematosus, Oxsoralen-ultra/Methoxsalen Capsule should not be used without consulting of doctor.

If you have suffering to the problem of Porphyria, Oxsoralen-ultra/Methoxsalen Capsule should not be used without consulting of doctor.

If you have suffering to the problem of Skin cancer, Oxsoralen-ultra/Methoxsalen Capsule should not be used without consulting of doctor.

If you have suffering to the problem of Liver disease, Oxsoralen-ultra/Methoxsalen Capsule should not be used without consulting of doctor.

Under which storage conditions Oxsoralen-ultra/Methoxsalen should be kept?

Oxsoralen-ultra/Methoxsalen should be stored in cupboard at room temperature, away from heat, moisture, and direct light. Do not store Oxsoralen-ultra/Methoxsalen Capsule in the bathroom, near the kitchen sink, or in other damp places. Keep always Oxsoralen-ultra/Methoxsalen medicine out of the reach of children.

Major drug Manufacturers

  • Valeant Pharmaceuticals
  • Pharmacia Biotech
  • Therakos, Inc
  • Derma Tech
  • 3M Pharmaceuticals
  • Canderm Pharmacal

Similar drugs Oxsoralen-ultra/Methoxsalen

  • Methoxsalen
  • 8-MOP
  • Oxsoralen Topical
  • Uvadex
  • Ultramop (Canada)
  • Oxsoralen
  • Ultra MOP
  • Oxsoralen Lotion (Canada)
  • UltraMOP Lotion (Canada)

From where can one get Oxsoralen-ultra/Methoxsalen?

Anyone can buy Oxsoralen-ultra/Methoxsalen from Online Canadian Pharmacy, which is available at a discounted price, 50% off, in Canada, and the best way to get Oxsoralen-ultra/Methoxsalen is by logging on to http://www.canadiandrugswholesale.com for online orders. This pharmacy provides you with drugs at cheap and affordable prices. One can order the medicine and pay through VISA, MasterCard or international money order.

Why to buy Oxsoralen-ultra/Methoxsalen drug from Canada?

It is cheaper to buy Oxsoralen-ultra/Methoxsalen from Online Canadian Pharmacy, because Canadian government regulates the prices of Oxsoralen-ultra/Methoxsalen and also because of the very common reason of exchange rate. Since, the Canadian dollar is cheaper as compared to the US Dollars, so one can buy more Oxsoralen-ultra/Methoxsalen from Canada, there by saving a lot of money.

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