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Agrylin
Agrylin consists of a compound called Anagrelide HCL, and is used for the treatment of essential thrombocythemia, a life-threatening condition characterized by elevated blood platelet counts. Agrylin/Anagrelide comes in the form of tablets and is being manufactured by Shire Pharmaceuticals.
What are the major disorders for which Agrylin/Anagrelide may be Used?
Agrylin/Anagrelide is the first drug approved for the treatment of essential thrombocythemia, a life-threatening condition characterized by elevated blood platelet counts.
ET i.e. essential thrombocythemia is one of the six myeloproliferative diseases (MPD) in which the bone marrow makes too many of certain types of blood cells. Bone marrow, the spongy tissue inside the large bones in the body, makes red blood cells (which carry oxygen to body tissues), white blood cells (which fight infection), and platelets (which make the blood clot). It is characterized by a condition wherein the platelet count is much higher than normal without any known cause. Other cells in the blood are normal. The extra platelets make it hard for the blood to flow normally. Too many platelets make normal clotting of blood difficult.
Their may be many symptoms for thrombocythemia, however, each individual may experience symptoms differently. Some of these include increased blood clots in arteries and veins; bleeding; bruising easily; bleeding from the nose, gums, gastrointestinal tract
bloody stools; hemorrhaging after injury or surgery; weakness, and enlarged lymph nodes. The symptoms of thrombocythemia may resemble other blood disorders or medical problems. Hence a doctor can only identify the problem.
If this problem is not treated well in time, it may become a life threatening issue. There are number of medicines available for curing this problem, and Agrylin/Anagrelide is the one medicine that has been approved.
How Agrylin works?
Agrylin/Anagrelide is used to decrease the number of platelets in the blood of patients whose platelet count is too high. It has not been found out as to how Agrylin works in the body to reduce your platelet count. However, Agrylin basically focuses on the platelets. Agrylin may not have a clinically significant effect on other cells in the blood, such as white cells, which help fight infection, and has no clinically significant effect on red cells, which carry oxygen throughout your body.
In addition, Agrylin does not affect the body's natural processes to clot blood when needed. Agrylin, therefore, lowers your platelet count and offers the safety advantages of platelet-specific action.
Is any prescription required to get Agrylin?
Agrylin/Anagrelide must not be used without the consultation of a doctor. Agrylin may or may not be suitable or a particular individual and as Agrylin is used for a condition which may be life threatening, so its suitability depends from individual to individual. Hence, Agrylin/Anagrelide should be taken under doctor’s guidance.
Dosage of Agrylin?
Agrylin/Anagrelide comes as a capsule and Agrylin is usually taken two to four times a day. It is best to take Agrylin/anagrelide empty stomach for best results. However, its exact dosage can only be identified by a medical practitioner, as the problem is generally life long.
What is the minimum duration for which Agrylin should be taken?
No specific time period has been identified for the use of Agrylin, and it depends from person to person depending upon the situation. Also, the intake of Agrylin must not be stopped even if the symptoms seem to diminish, as the problem may not have been cured completely. It is advisable to consult a doctor for the exact duration for which Agrylin should be used.
Are there any side effects of Agrylin?
- Reduction in white blood cells
- Reduction in red blood cells
- Headache
- Fast heart beats
- Diarrhea
- Weakness
- Nausea
- Dizziness
- Gastric trouble
Under what circumstances should Agrylin not be used?
- If one is allergic to Agrylin/Anagrelide or any other medicine.
- Agrylin should not be used by females who are pregnant or are breast-feeding.
- Agrylin should be taken with care if one has or have ever had a blood disorder; high or low blood pressure; or heart, liver, or kidney disease.
- If one is planning to have a surgery one must inform the doctor about the use of Agrylin/Anagrelide.
Under which storage conditions Agrylin should be kept?
Agrylin/Anagrelide should be store at room temperature away from moisture and heat. Also, Agrylin should be thrown away if it has reached its expiry date.
Major Drug (Agrylin and other similar drug) Manufacturers
- Amgen
- Novartis
- Schering-Plough
- Celltech
- Abbott
- Goldshield
- Pharmacia
- Shire Pharmaceuticals
Similar Drugs
- Neupogen (Amgen)
- Molgramostim (Novartis, Schering-Plough)
- Feospan (Celltech)
- Ferrograd C (Abbott)
- Fersaday (Goldshield)
- Fersamal (Goldshield)
- Galfer (Galen)
- Refolinon (Pharmacia)
- Desferal (Novartis)
- Lenograstim (Chugai)
- Leucomax (Novartis, Schering-Plough)
From where can one get Agrylin?
Anyone can buy Agrylin/Anagrelide from Online Canadian Pharmacy, which is available at a discounted price, 50% off, in Canada, and the best way to get Agrylin is by logging on to http://www.canadiandrugswholesale.com for online orders. This pharmacy provides you with drugs at cheap and affordable prices. One can order the medicine and pay through VISA, MasterCard or international money order.
Why to buy Agrylin drug from Canada?
It is cheaper to buy Agrylin/Anagrelide from Online Canadian Pharmacy, because Canadian government regulates the prices of Agrylin and also because of the very common reason of exchange rate. Since, the Canadian dollar is cheaper as compared to the US Dollars, so one can buy more Agrylin from Canada, thereby saving a lot of money.
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